Dando la vuelta completa.

Cuando comencé psiquiatría, a mediados de los ochenta, el uso de los neurolépticos era el non plus ultra de la especialidad - la revolución psicofarmacológica estaba en su momento de máximo esplendor y los neo-kraepelinianos controlaban el panorama psiquiátrico (Los psiquiatras "Mindless" de L Eisenberg triunfaban sobre los psiquiatras "Brainless" de décadas anteriores). Parece que con esta editorial en el número de este mes de Archives of General Psychiatry, hemos dado el "full circle"; la conclusión del editorialista es explícita:

"A classic maxim in clinical medicine is to treat the patient, not the laboratory test—or in this case, the MRI. Thus, the findings of Ho and colleagues should not be construed as an indication for discontinuing the use of antipsychotic medications as a treatment for schizophrenia. But they do highlight the need to closely monitor the benefits and adverse effects of these medications in individual patients, to prescribe the minimal amount needed to achieve the therapeutic goal, to consider the addition of nonpharmacological approaches that may improve outcomes, and to continue the pursuit of new antipsychotic medications with different mechanisms of action and more favorable benefit to harm ratios."

Antipsychotic Medications and Brain Volume: Do We Have Cause for Concern? [Editorial]